Most Common IV Infusion Vitamins: What You Should Know

IV vitamin therapy is an excellent way to help your patients feel better faster. IV hydration helps detoxify the body, eliminating free radicals that contribute to impaired immune function. The right balance of electrolytes, fluids, vitamins, and antioxidants helps combat fatigue and low energy symptoms.

B vitamins help increase energy by converting food into energy. Amino acids, antioxidants, minerals, and vitamins stimulate fat metabolism and muscle repair and reduce inflammation, giving your clients the endurance boost they may need to work out and enhance post-workout recovery (Wells, 2020).

Do you have clients that suffer from dry skin and hair from living in a dry climate like Colorado? The infusion example below (Figure A) is a nice blend for hair, skin, and nails. Biotin, also known as B7, can help maintain the health of the nervous system, liver, eyes, hair, and skin. Biotin aids fat metabolism, which is vital for the formation of new tissue.

Glutathione is a powerful antioxidant that supports a healthy immune system by protecting cells from free radical damage and supporting optimal cell health and a healthy liver. Vitamin C (Ascorbic Acid) boosts the immune system while helping with inflammation.

B-complex is a great immune system booster and digestion regulator; it aids in fighting fatigue (Empower Pharmacy, n.d.b,c,d,h). B-12 (Hydroxocobalamin) plays a crucial role in metabolizing serotonin, which regulates your mood. It also helps to burn fat, turn carbohydrates into energy, and manufacture new proteins (Empower Pharmacy, n.d.e. & PDR, n.d.).

What are the Most Common IV Infusion Vitamins and Ingredients?

The most common IV insulin vitamins are Vitamin B-Complex, and Vitamin C. IV infusion therapy is a popular way to deliver high doses of vitamins, minerals, and antioxidants directly into the bloodstream to address deficiencies, boost energy, and support overall health.

Intravenous (IV) vitamin therapy may consist of a single vitamin or a combination of vitamins and minerals. Common components include:

Saline Solution

The foundation of every IV infusion is a bag of sterile saline solution made up of 0.9% sodium chloride (NaCl) and water. This provides hydration and helps deliver the other nutrients into the veins.

Vitamin B-Complex

B vitamins help convert food into energy and form red blood cells. They include:

• Thiamin (B1) - Essential for energy production, carbohydrate metabolism, and nerve function

• Riboflavin (B2) - Crucial for energy production and antioxidant regeneration

• Niacin (B3) - Important for circulation, nerve function, and digestion

• Pantothenic Acid (B5) - Aids in the breakdown of fats and carbohydrates

• Pyridoxine (B6) - Necessary for protein metabolism and red blood cell formation

• Biotin (B7) - Supports the health of the skin, hair, nails, and nervous system

• Folate (B9) - Essential for cell growth and development

• Cobalamin (B12) - Plays a key role in energy production, red blood cell formation, and DNA synthesis

Vitamin C (Ascorbic Acid)

Vitamin C is a powerful antioxidant that boosts the immune system and helps with inflammation. It may also help with fatigue and athletic performance.

IV vitamin C can significantly support cardiovascular health by rapidly increasing blood concentrations, which may lower blood pressure, especially in pre-hypertensive individuals. High doses of IV vitamin C have been shown to reduce mean blood pressure and improve arterial health by combating oxidative stress and inflammation.

Glutathione

Glutathione is a potent antioxidant that supports a healthy immune system by protecting cells from free radical damage. It also aids in detoxification and liver health.

Glutathione IV therapy is beneficial for respiratory health as it combats oxidative stress and inflammation in the lungs, helping to alleviate symptoms of conditions like asthma and COPD. In the context of glutathione in respiratory health and COVID-19, enhancing glutathione levels through IV therapy can improve lung function, support recovery from respiratory illnesses, and mitigate excessive inflammatory responses, particularly in cases of severe COVID-19. Additionally, glutathione aids in detoxifying the lungs from harmful pollutants, making it a promising treatment option for chronic lung disease management, especially during the ongoing challenges posed by respiratory infections.

Magnesium

Magnesium enhances the nervous and muscular systems to aid in recovery and help decrease anxiety. It is a common ingredient in the popular "Myers' Cocktail" IV infusion.

Calcium Gluconate

Calcium is essential for bone health, nerve conduction, blood coagulation, and heart function.

Other Ingredients

Other vitamins, minerals and amino acids like zinc, selenium, taurine, and L-arginine may also be included to target specific health goals like sports performance, skin/hair/nail health, and cardiovascular support.

While IV vitamin therapy can help address deficiencies and provide a quick boost, it does carry some risks like nutrient imbalances, toxicity, and IV-related complications. It's important to consult with a qualified healthcare provider before starting any IV therapy regimen.

Figure A: Example Infusion Recipe

• 1L NS

• Ascorbic Acid- 2 grams (500 mg/ml): 4 ml

• B Complex – (B1- 100, B2-2, B3-100, B5-2, B6- 2 mg/ml): 2 ml

• Biotin 60 mcg (10mg/ml): 0.6 ml

• B12 (Hydroxocobalamin) 2mg (2 mg/ml): 2 ml

• Glutathione 200 mg (200 mg/ml): 1 ml

  • Give after the infusion is complete. Mix in a 10 ml saline syringe and push over 3-5 minutes directly into the IV closest to the patient arm. Flush with 10 ml of normal saline.

The Myers’ Drip is a famous infusion recipe created by Dr. John Myers. It is one of the most used and studied IV therapy combinations to reduce pain, inflammation, and muscle cramping while boosting energy and immunity. Dr. Myers noted in his studies that it improved athletic performance and showed positive results in patients with migraines, fatigue, respiratory tract infections, asthma, cardiovascular disease, and seasonal allergies. It contains Magnesium, B Complex, B12, Ascorbic Acid, and Calcium Gluconate (Gaby, 2002). Magnesium enhances the nervous and muscular systems to aid in recovery and help decrease anxiety. Calcium Gluconate’s role in building bones and supporting their health is well known, but it is also essential for nerve conduction, blood coagulation, and electrical conduction in the muscular tissue of the heart (Empower Pharma, n.d.,f).

Other minerals and vitamins can aid in recovery after a workout or boost endurance before exercise. L-Arginine may enhance exercise performance by increasing nitric oxide in the body, which improves blood flow and oxygenation to muscles. It also stimulates the release of growth hormones, insulin, and other substances. Taurine may increase heart health by reducing high blood pressure and decreasing resistance to blood flow in your blood vessel walls. A study showed a decrease in inflammation, fatigue, and muscle damage during a workout. Taurine can also remove waste. Another study showed Taurine caused muscles to work harder and for longer and increased the muscles’ ability to contract and produce force (Empower Pharmacy, n.d.a,g).

Do you have clients feeling rundown or getting over a cold? You might see infusions that contain Zinc, Glutathione, and Ascorbic Acid. Zinc reduces oxidative stress and inflammatory proteins and can reduce your risk of chronic inflammation. Zinc plays a critical role in immune function, and research has shown that people who take zinc during a cold have reduced symptoms and a faster recovery. Your body needs zinc to create new cells, especially fiber-like tissues and collagen in your skin. Zinc can support wound healing by helping these types of cells regenerate after an injury (Empower Pharmacy, n.d.b,d,i).

These Vitamin Infusions and numerous combination recipes can offer many benefits to your clients. You can customize the recipe based on the symptoms your client wants to address, as most vitamins are compatible. Vitamin infusions are an easy and fast way to help your clients feel their best!

See the table below for more information about contraindications, side effects, toxicity, and storage temperature.

​Vitamin	Contraindications	​Side Effects	​S/Sx of Toxicity	Benefits
Magnesium Chloride Storage Temp: 68-77F ***Can be mixed with all vitamins in this table	​Pregnant or breastfeeding Heart or kidney disease On a magnesium supplement at home Neuromuscular disorders such as myasthenia gravis Taking Mg with muscle relaxers at the same time may increase side effects	​Flushing Sweating Abdominal cramping Diarrhea May cause lower blood pressure or decreased respiratory rate	Hypotension Nausea Vomiting Diarrhea Facial flushing Retention of urine Ileus Respiratory depression Muscle weakness Cardiac arrest	Enhances the nervous and muscular system to aid in recovery and help decrease anxiety
​Ascorbic acid Storage Temp: 36-46F ***Can be mixed with all vitamins in this table	​If receiving chemotherapy, the client should notify their oncologist Pregnant or breastfeeding With Diabetes mellitus, it may cause falsely decreased glucose concentrations Hemochromatosis may be at risk for iron toxicity If on an iron supplement, may have decreased absorption if receiving a high dose ascorbic acid therapy Renal diseases are at increased risk for renal stones following large doses of ascorbic acid	​Diarrhea Abdominal cramping GI upset	​Flushing Nausea Vomiting Headache Abdominal cramps Dizziness Diarrhea GI upset	​Boosts the immune system while helping with inflammation
​B Complex B1 (thiamine) B2 (riboflavin) B3 (niacinamide) B5 (dexpanthenol) B6 (pyridoxine) Storage Temp: 36-46F ***Can be mixed with all vitamins in this table	​Pregnant or breastfeeding	​Diarrhea Feeling as though the body is swollen	​Anxiety Itching Respiratory distress Nausea Vomiting Abdominal pain Anorexia Headache Irritability Tremor Palpitations Skin flushing Confirm no previous adverse vitamin B or vitamin H allergies	Great immune system booster Digestion regulator Aids in fighting fatigue Necessary for general healthy skin and muscle, brain, and nerve functionality
​B6 (Pyridoxine in B Complex) Storage Temp: 36-46F ***Can be mixed with all vitamins in this table	​Sensitivity to ingredients Pregnant or breastfeeding	​Lower blood pressure May impact blood glucose May increase the risk of bleeding May cause GI upset May cause tingling or numbness	​Anxiety Itching Respiratory distress Nausea Vomiting Abdominal pain Anorexia Headache Irritability Tremor Palpitations Skin flushing	​Great immune system booster Digestion regulator Aids in fighting fatigue Necessary for general healthy skin, muscle, brain, and nerve functionality
​B12 (Hydroxocobalamin) Storage Temp: 68-77F ***Can be mixed with all vitamins in this table	​Pregnant or breastfeeding Hypersensitivity to cobalt moiety or cobalamin molecule due to risk of anaphylaxis Leber’s disease Severe megaloblastic anemia	​Diarrhea Itching Swelling of body Cannot be given more than once per week; ask when their last dose occurred	Anaphylaxis, death Pulmonary edema Polycythemia vera Congestive heart failure Peripheral vascular thrombosis	​Plays a crucial role in metabolizing serotonin, which is responsible for regulating your mood Helps to burn fat and turn carbohydrates into energy and manufacture new proteins
​Calcium Gluconate Storage Temp: 68-77F ***Can be mixed with all vitamins in this table	​Pregnant or breastfeeding Ventricular fibrillation Hypercalcemia Chronic kidney failure	​May cause a change in heart rhythms	​May decrease blood pressure or cause a change in heart rhythms May cause tingling or warm sensations GI upset or constipation	​Has a role in building bones and supporting their health Important for nerve conduction, blood coagulation, and electrical conduction in the muscular tissue of the heart
​Glutathione Storage Temp: 36-46F ***Can be mixed with all vitamins in this table	​Caution with a Sulfa allergy! Pregnant or breastfeeding Caution in those with a history of asthma Must be given as IV push slowly over 3-5 minutes, dilute with NS push; not to be given in NS 1L bag If the client tolerates one dose of 200mg Glutathione, subsequent doses may be increased to 400 mg	​May exacerbate asthma symptoms	​None noted	​It is a powerful antioxidant that supports a healthy immune system by protecting cells from free radical damage and supporting optimal cell health and a healthy liver
​Taurine Storage Temp: 68-77F ***Can be mixed with all vitamins in this table	​Pregnant or breastfeeding Few adverse effects in doses up to 3g	​Can lower blood pressure; use caution if on blood pressure medications	​None noted	​Increases heart health by reducing high blood pressure and the resistance to blood flow in your blood vessel walls Decreases inflammation, fatigue, and muscle damage during a workout Removes waste products that lead to fatigue and cause muscle burn, protecting muscles from cell damage and oxidative stress Causes muscles to work harder and for longer, increasing the muscles’ ability to contract and produce force
​Biotin Storage Temp: 68-77F ***Can be mixed with all vitamins in this table	​Pregnant or breastfeeding May falsely cause low troponin Medications/ Substances that may decrease efficacy of biotin Atropine, hyoscyamine, phenobarbital, scopolamine, belladonna alkaloids, ergotamine, carbamazepine, excessive alcohol, raw egg white, fosphenytoin, phenytoin, and primidone	​None Noted	​None Noted	​Hair, skin, and nail health Can help depression or peripheral neuropathy
​L-Arginine Storage Temp: 68-77F ***Can be mixed with all vitamins in this table	Guanidinoacetate methyltransferase deficiency (GAMT): People with this inherited condition are unable to convert arginine and other similar chemicals into creatine; to prevent complications from this condition, avoid L-arginine supplements In renal or hepatic impairment and electrolyte imbalances	​May cause stomach pain, bloating, and diarrhea Low blood pressure Flushing Headache Injection site skin irritation (If irritation at IV site, slow down rate of drip)	Maculopapular rash with reddening and swelling of face-stop infusion (may need to administer Benadryl)	​May enhance exercise performance by increasing nitric oxide in the body, which improves blood flow and oxygenation to muscles Stimulates the release of growth hormone, insulin, and other substances in the body
​Zinc Sulfate Storage Temp: 68-77F ***Can be mixed with all vitamins in this table	​Pregnant or breastfeeding Caution in clients with renal impairment Caution with clients taking tetracyclines, quinolones, penicillins; zinc inhibits absorption if taken concurrently Caution with sulfa allergies Too much zinc can reduce copper levels	​Nausea Vomiting Gastric irritation Elevation of serum alkaline phosphate, amylase, and lipase	​Hematuria Hematemesis Acute tubular necrosis Diarrhea.	​Reduces oxidative stress and inflammatory proteins Can reduce your risk of chronic inflammation Plays a critical role in immune function, and research has shown that people who take zinc during a cold have reduced symptoms and a faster recovery The body needs zinc to create new cells, especially fiber-like tissues and collagen in your skin; supports wound healing by helping these types of cells regenerate after an injury

What Are the Most Popular Iv Therapy Recipes?

Here are some of the most sought-after IV infusion recipes that cater to various health needs:

1. Myers' Cocktail

The Myers' Cocktail is the most renowned IV infusion, designed to boost energy and support overall health. It typically includes:

• Vitamin C - A powerful antioxidant that supports immune function.

• B Vitamins (including B12 and B3) - Essential for energy production and red blood cell formation.

• Magnesium - Helps with muscle function and reduces fatigue.

• Calcium - Important for bone health and nerve function.

• Zinc - Supports immune health.

• Selenium - Acts as an antioxidant.

• Glutathione - A potent detoxifier and antioxidant.

This cocktail is often used to alleviate conditions such as migraines, chronic fatigue, and seasonal allergies. The Myer's Cocktail is commonly prescribed for pregnant mothers experiencing morning sickness. This IV package can help alleviate nausea, vomiting, and dehydration associated with morning sickness.

2. Immune Booster

This infusion is tailored to enhance the immune system, particularly during cold and flu season. It typically contains:

• Vitamin C - For cellular support and immune enhancement.

• Zinc - To bolster the immune response.

• Glutathione - For its antioxidant properties.

The Immune Booster is ideal for those feeling run down or exposed to illness.

3. Hydration and Recovery Blend (Quench)

Ideal for post-exercise recovery or after a night out, this IV therapy includes:

• Electrolytes - To replenish lost fluids.

• Vitamin C - For detoxification and hydration.

• B Complex Vitamins - To boost energy levels and enhance recovery.

The Quench infusion helps restore hydration and energy, making it a popular choice for athletes and those recovering from dehydration.

4. NAD+ Infusion

Nicotinamide adenine dinucleotide (NAD+) is crucial for energy metabolism and cellular repair. This infusion is often used for:

• Enhancing mental clarity and focus.

• Supporting energy production.

• Promoting recovery from addiction.

NAD+ infusions are particularly beneficial for those looking to improve their overall cognitive function and energy levels.

5. Skinny and Energized

This infusion is aimed at those looking to support weight loss and boost metabolism. It typically includes:

• B12 and B Complex Vitamins - To enhance metabolism and energy.

• Amino Acids - To support muscle recovery and fat burning.

The Skinny and Energized infusion is popular among individuals pursuing weight loss goals.

The Inner Beauty infusion helps improve skin tone and overall complexion, making it a favorite for those seeking aesthetic benefits.

Pros and Cons of Vitamin IV Therapy

Pros of Vitamin IV Therapy

1. Rapid Nutrient Absorption: Immediate delivery into the bloodstream.

2. Increased Energy Levels: Boosts energy and overall well-being.

3. Customized Treatments: Tailored to individual health needs.

4. Hydration: Quickly rehydrates the body.

5. Potential Health Benefits: Alleviates symptoms of various conditions.

6. Higher Concentrations of Nutrients: More effective than oral supplements.

Cons of Vitamin IV Therapy

1. Risk of Overdose: Potential for toxicity with high doses.

2. Possible Side Effects: Risks include infection, bruising, and allergic reactions.

3. Not a Long-Term Solution: Should not replace a balanced diet.

4. Cost: Treatments can be expensive.

5. Limited Regulation: Varying quality and safety among providers.

6. Immediate Reactions: Possible adverse reactions, especially with untrained personnel.

References

Gaby, A.R. (2002). Intravenous nutrient therapy: the "Myers' cocktail". Altern Med Rev, 7(5):389-403. PMID: 12410623. https://pubmed.ncbi.nlm.nih.gov/12410623/

Wells, C., Butcher, R., & McCormack, S. (2020). Intravenous Multivitamin Therapy Use in Hospital or Outpatient Settings: A Review of Clinical Effectiveness and Guidelines [Internet]. Canadian Agency for Drugs and Technologies in Health. PMID: 33523616.